A stranger in a strange place, the player's hero must learn the layout of the land, seek out the local head of each Syndicate gang, and eliminate its leader. In retaliation, the Syndicate captures the player's character, a high-ranking member of the Third Street gang, and takes him far from the safety of his Stillwater home turf, to the city of Steelport. The Saints decline, choosing independence over new allies, and thus make a new enemy instead. Trouble begins as an organization of criminal gangs from other cities, known as the Syndicate, invites the Saints to join. A municipal treasury's worth of wealth and power at their disposal, the Saints now have easy access to over-armed tanks and laser-equipped experimental aircraft, as well as any car they happen to fancy on the busy city streets.Much of the game's main narrative, however, takes place away from the relative safety of Stillwater.

No longer struggling against rival crime families and meddling authorities, the Third Street Saints now rule the city of Stillwater - and have everything to lose.Persevering in their gangland domination through the first two urban adventures, the Saints have risen from the criminal underworld to become a household brand name - and a well-marketed one at that, with t-shirts, bobble-head dolls, and other tchotchke eagerly bought up by the amenable (if not adoring) Stillwater populace. Following the tread marks of its predecessors, Saints Row: The Third is an open-world action-adventure, in an urban setting of speed and violence.

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